GenoMed Connect

Metabolic Reprogramming in Brain Metastases: Integrating Spatial Omics with Non-Spatial Mechanistic Evidence

Vol. 3

Brain metastases (BrMs) develop within a metabolically specialized environment, where nutrient availability and interactions with neural, vascular and immune cells can influence tumor growth. Bulk and single-cell studies...

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Noncoding RNA-Mediated Control of HbF Switching: From Molecular Mechanisms to Clinical Translation

Vol. 3

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July 9, 2026

Unveiling the Fourth Meningeal Layer: Implications for Brain Structure, Function, and Neurological Disease

Vol. 3

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July 8, 2026

Dynamic Virtual Tumor Cells Powered by Spatial Omics for Translational Oncology

Vol. 3

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June 12, 2026

Spatial Profiling of the Head and Neck Squamous Cell Carcinoma Microenvironment: Reshaping Our Understanding and Therapeutic Opportunities

Vol. 3

Head and neck squamous cell carcinoma (HNSCC) is characterized by a highly heterogeneous tumor microenvironment (TME), which plays a critical role in disease progression and therapeutic resistance. The emergence of spati...

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June 11, 2026

Regional Differences in Brain Tumors: Genetic Drivers and Spatial Molecular Ecology

Vol. 3

The human brain exhibits marked regional specialization in cellular composition, gene expression, and tissue architecture. Growing evidence suggests that these spatial differences influence both the anatomical distributi...

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June 5, 2026

Spatial Heterogeneity of TMEs in cHL and PDAC: Mechanistic Insights and Therapeutic Perspectives

Vol. 3

The tumor microenvironment (TME) is a critical niche that influences tumor progression and the development of therapeutic resistance. Spatial omics technologies enable in situ investigation of cellular ecology and interc...

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May 25, 2026

Y-STR Mutation Patterns in North Indian Male Relatives at 16 Loci: A Preliminary Study

Vol. 3

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