Cancer Research and Therapy Connect

December 31, 2025

Covalent BH3-Mimetics and PROTACs: Targeting BCL2 Family for Precision Apoptosis Induction

Vol. 1

The BCL2 family of proteins serves as a central regulator of mitochondrial outer membrane permeabilization (MOMP) and intrinsic apoptosis, with anti-apoptotic members such as BCL2, BCL-XL, and MCL1 frequently overexpress...

0 citations

December 30, 2025

Preface

Vol. 1

It is my honor as Editor-in-Chief to present the first volume of Cancer Immunology Connect, a new peer-reviewed journal focused on the rapidly advancing fields of cancer immunology and immunotherapy. The aim of this firs...

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June 17, 2025

The Intratumor Microbiome: An Untapped Avenue for Translational Applications in Cancer Immunotherapeutics

Vol. 1

0 citations

May 23, 2025

Fatty Allies: How Short-Chain Fatty Acids Turn the Tumor Microenvironment Against Cancer

Vol. 1

5 citations

April 15, 2025

Association of Expression of Immune Checkpoints in Tumor-Infiltrating CD4+ T Lymphocytes with Disease-Free Survival in Colorectal Cancer Patients

Vol. 1

0 citations

March 21, 2025

Characteristics of Tumor Infiltrating Lymphocytes in Patients with Benign and Malignant Sinonasal Neoplasms

Vol. 1

Introduction. Tumor infiltrating lymphocytes are a major component of sinonasal neoplasms, actively populating tumor tissue, yet their role remains poorly understood. The aim is to characterize subsets and functional pro...

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March 19, 2025

Soluble Biomarkers as Predictors of Response to Immunotherapy in Non-Small Cell Lung Cancer (NSCLC)-Insights from the Tumor Microenvironment Perspective

Vol. 1

Lung cancer is the major cause of mortality worldwide with non-small cell lung cancer (NSCLC) contributing to 85% of the cases. FDA-approved immune checkpoint inhibitors (ICI), anti-PD-1, and anti-PD-L1 are widely used a...

1 citation

February 11, 2025

CRISPR-Cas9 is Revolutionizing AML Treatment as a Novel Therapy

Vol. 1

This review explores the progression of CRISPR-Cas9 genome editing technology in gene therapy for acute myeloid leukemia. Acute Myeloid Leukemia, a serious blood cancer, presents formidable treatment obstacles and a dism...

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January 8, 2025

Chronic Myelomonocytic Leukemia Relapse After Transplant

Vol. 1

Relapse of Chronic Myelomonocytic Leukemia after allogeneic hematopoietic stem cell transplantation remains a significant challenge, with relapse rates reaching up to 50%, contributing to poor survival outcomes. This pap...

0 citations

October 21, 2024

Neoantigen-Based Cancer Vaccines: Current Innovations, Challenges and Future Directions in Personalized Immunotherapy

Vol. 1

10 citations